No, as the term "irreversible" means--though "irrevocable," or cannot be revoked, is the more common term--the trust cannot be modified or undone.
However, if a trustee is mentally incompetent, a person with an interest in the trust (e.g. a beneficiary) may bring a legal action to have the trustee removed and another trustee appointed. Such an action is much more procedurally and legally complex than, say, suing in small claims court: a beneficiary wanting to do this should retain a trusts and estates attorney to help.
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